There are a few ways to use DMT. The most well-known is to drink it in the form of ayahuasca — but you can smoke or vape it too.
Vaping DMT is sometimes referred to as a “business trip”. This name comes from the implication that DMT used in this way produces a powerful but short-lived experience. The whole trip lasts just 20 to 30 minutes in total.
For comparison, LSD, ayahuasca, and magic mushrooms last anywhere from 6 to 10 hours.
In this guide, we’ll cover everything you need to know about using DMT vape pens and their Benefits.
What is DMT?
DMT stands for dimethyltryptamine — it’s a powerful hallucinogenic compound found in a variety of plants and animals. Our own brains even make DMT — albeit in very small concentrations. It’s thought that DMT contributes to our ability to dream and may be involved with other aspects of conscious and unconscious thought.
This compound is a strong psychedelic, capable of injecting you into what feels like another dimension entirely. Some people even report meeting entities (AKA machine elves) with breakthrough DMT experiences.
How Does DMT Work?
DMT interacts with the 5-HT2A receptors within the brain. It’s thought that the activation of this receptor is the primary mechanism used by DMT to produce its hallucinogenic and introspective effects. This is the same mechanism used by other classical psychedelics, including LSD, psilocybin, and mescaline.
Early research has discovered psychedelics like DMT can inhibit what’s known as the default mode network (DMN). This is a series of interconnected brain regions that maintain our grasp on reality and regulate other brain regions. When we take DMT, the default mode network is temporarily inhibited, allowing other brain regions to interact that wouldn’t normally. The term used to describe this is “entropy,” which was borrowed from the field of thermodynamics.
Higher entropy levels are associated with type II consciousness, more creativity, out-of-the-box thinking, and hallucinogenic episodes.
What is a DMT Vape Pen?
A DMT vape pen combines either N,N,DMT or 5-MeO-DMT with an e-liquid base. It’s then added to a standard vaporizer, just like the type you’ll find from cannabis manufacturers.
Vape pens are designed to heat the contents without burning them. The DMT and its base agent (usually e-liquid) are heated just enough to convert into a vapor which can then enter the lungs for absorption. Vape pens typically heat the active ingredients to around 400ºF (204ºC).
DMT can also be smoked, but the high heat (over 1500ºF or 900ºC) destroys a lot of the viable DMT and produces potentially harmful byproducts.
- N,N,DMT — this is the type of DMT most commonly found in plants. It’s the active ingredient in the traditional Shamanic brew known as ayahuasca.
- 5-MeO-DMT — this is the form of DMT found in the venom of the Bufo alvarius toad, as well as a few species of plants and fungi.
The Effects of DMT Vape Pens
DMT vape pens offer a fast-acting psychedelic experience. Within seconds of inhalation, users typically report:
- Intense Visuals – Vivid colors, geometric patterns, and rapid transformations of the environment.
- Altered Perception of Time & Space – Many users describe feeling disconnected from reality, as if entering another dimension.
- Ego Dissolution – A sensation of merging with the universe or experiencing profound insights.
- Emotional Shifts – Euphoria, awe, or even overwhelming introspection.
What Are the Benefits of DMT Vape Pens?
- Mental Clarity & Insight – Many report deep personal revelations.
- Mood Enhancement – Users often feel more connected and uplifted after a trip.
- Convenience & Discreetness – Unlike traditional DMT consumption methods, vape pens offer an easy-to-use and portable option.
- Simple to use — Breakthrough experiences are available to virtually everybody. When used responsibly, this may offer a substantial capacity for healing.
- Ability to control the dose — By regulating how many hits you take and the amount of time you hold the vapor in your lungs, you can control the intensity of effects with a reasonable degree of accuracy.
- Less harsh on your throat and lungs than smoking — Let’s be clear, vaping DMT is going to be harsh, but it’s far less harsh than smoking DMT.
How to Use a DMT Vape Pen
The whole point of a DMT vape is that it’s simple to use. Nevertheless, there are a few steps to follow to get the most efficient hit from your vape.
Step 1: Shake the Pen
Always give the pen a good shake before you use it. The DMT will tend to separate from the e-liquid base, so if you skip this step, you will either get a hit of pure DMT or pure e-liquid.
Step 2: Take one Long Inhale, and Exhale Completely
This does two things; it calms you down before the hit, which is going to help reduce the chances of having a challenging or anxious experience. Secondly, it prepares you to take a longer, deeper breath during the next step, ultimately making the DMT more efficient.
Step 3: Take a Deep Inhale
Don’t rush it — inhale the vapor from the device slowly. It’s going to be pretty harsh, so taking longer, slower breaths will cut back on some of this harshness. Once you’ve taken a full inhale, release the pen and take one more inhale to bring all the vapor into the lungs.
Step 4: Hold Your Breath for a Few Seconds Before Exhaling
The DMT will immediately start absorbing through your lungs. Keeping the vapor in the lungs for a few seconds before exhaling allows you to get more efficiency from the DMT you’re using. The longer you hold your breath, the stronger the hit will be.
Step 5: Repeat as Necessary
Depending on the potency of your pen, the amount of vapor you inhaled, and the time you held the vapor in your lungs, you may need to take a few hits to reach breakthrough levels.
Dosage Guidelines
Using DMT vape pens responsibly is crucial to ensuring a positive and safe experience. Typical dosages include:
- Low Dose (5-10 mg): Mild visual effects, slight mood shifts
- Moderate Dose (15-30 mg): Strong visuals, altered perceptio
- High Dose (30+ mg): Intense “breakthrough” experience
It’s recommended to start with a small puff to gauge your tolerance before increasing the dosage.
Setting & Mindset (The 5 Key Factors)
To ensure a safe and meaningful trip, consider the following factors:
1)Set (Mindset): A calm and positive state of mind reduces the risk of a bad trip.
2)Setting (Environment): Choose a safe, quiet, and familiar place.
3)Trip Sitter: Having a sober, trusted friend present can provide reassurance.
4)Intention: Set a purpose for your trip—self-discovery, healing, or creativity.
5)Breath Control: Deep, steady breathing helps manage intense experiences.
Summary
DMT pens provide an easy and efficient way to experience the profound effects of DMT. While they offer a unique and transformative journey, it’s crucial to understand their risks and use them responsibly. Whether you’re seeking self-exploration or a deep psychedelic experience, always prioritize safety, setting, and mindset.
