Does microdosing actually do anything, or is it a posh urban myth? A research team in is about to find out in the world’s first randomized, controlled clinical trial.

LSD has largely been ignored while the world gushes over legal marijuana and decriminalized magic mushrooms. But a new research project will assess whether the counterculture’s favorite psychedelic is just a hedonistic substance or a tried and true medical treatment. The clinical trial, at a University , will investigate whether LSD and psilocybin microdoses actually do anything microdoses actually do anything and if they do, whether those effects can translate to medical treatments. 

“The data looks promising, but it’s not clear yet… whether the risk-benefit ratio is there, and we’re not sure yet whether it might work over and above a good placebo,”

The study discovered that LSD works by connecting all parts of the brain together at once. The findings were so mind-blowing that Inverse awarded the study “Experiment of the Year” and noted that it would “fundamentally alter the future of an entire field.” drug addiction, LSD has made some serious strides over the decades, from Woodstock to modern medical clinics. Otherwise known as acid, LSD is known for causing hallucinations and fuzzy, feel-good thoughts, but it could also treat everything from PTSD to drug addiction to clinical depression. The same goes for psilocybin, the psychedelic component of “magic mushrooms.” 

If the project receives government approval, a team will conduct the world’s first randomized, controlled clinical trial for LSD and psilocybin microdosing.

Of course, this wouldn’t be the first study delving into LSD’s secrets. Last last year, researchers began the first placebo controlled trials for microdosing LSD. Over the past year, researchers began looking into the same thing, too, while American researchers published their LSD microdosing study results this summer. These ongoing studies are different from other trials because they’re not concerned with whether microdosing possesses medical efficacy, but rather whether microdosing generates real psychoactive effects or if it’s just placebo.

“Drug tests in pharmaceutical companies usually involve hundreds of people in each study across multiple studies and multiple centers in order the get the data that you need to say it works, that we have a really good side-effect profile, and we know how to do this in the safest possible manner,”  


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